Hepatomegaly is that the condition of getting associate degree enlarged liver. Its a non-specific medical sign having several causes, which might generally be countermined into infection, internal organ tumors, or disorder. Often, abnormality can present as associate degree abdominal mass. Depending on the cause, its going to generally gift in conjunction with jaundice. Symptoms having to try and do with abnormality will embrace many; among them the individual might expertise some weight loss, poor appetence and lethargy jaundice and bruising may also be present. Treatment of abnormality can vary depending on the reason behind the liver enlargement and thence correct diagnosing is that the primary concern. Within the case of auto-immune disease, prednisone and azathioprine is also used for treatment. Within the case of cancer the treatment choices embrace single-agent therapy and regional actinotherapy, additionally surgery is also associate degree choice in specific things. Meningococcal cluster C conjugate vaccines are employed in some cases. In primary biliary cirrhosis of the liver ursodeoxycholic acid helps the blood take away digestive juice which can increase survival in some affected people. Our target audience, readers and contributors are worldwide. Health Care Research invites an article to publish in the Journal of Nursing and Health Care.