Megaloblastic anemia is a type of anemia, a blood disorder in which the number of red blood cells is lower than normal. It is a condition in which the bone marrow produces unusually large, structurally abnormal, immature red blood cells. Megaloblastic anemia is caused when red blood cells are not produced properly. Because the cells are too large, they may not be able to exit the bone marrow to enter the bloodstream and deliver oxygen. The two most common causes of megaloblastic anemia are deficiencies of vitamin B-12 or folate. These two nutrients are necessary for producing healthy red blood cells. The most common symptom of megaloblastic anemia is fatigue. Symptoms can vary from person to person. Common symptoms include:
- shortness of breath
- muscle weakness
- abnormal paleness of the skin
- loss of appetite/weight loss
- fast heartbeat
- smooth or tender tongue
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