Congenital hypothyroidism may be a condition of hormone deficiency present at birth. If untreated for many months when birth, severe inborn glandular disease will cause growth failure and permanent intellectual incapacity. Treatment consists of a daily dose of hormone orally. As a result of the treatment is easy, effective, and cheap, nearly the entire developed world practices newborn screening to discover and treat inborn glandular disease within the 1st weeks of life. Infants born with inborn glandular disease could show no effects, or could show gentle effects that always go unrecognized as a problem: excessive sleeping, reduced interest in nursing, poor tone, low or cacophonous cry, rare viscous movements, exaggerated jaundice, and low temperature. If craniate deficiency was severe owing to complete absence of the secretor, physical options could embrace a bigger anterior opening, persistence of a posterior opening, a herniation, and an outsized tongue. Within the era before newborn screening, but 1/2 cases of severe glandular disease were recognized within the 1st month of life. Because the months proceeded, these babies would grow poorly and be delayed in their development. By many years archaic, they might show the recognizable facial and body options of hypothyroidism. Persistence of severe, untreated glandular disease resulted in severe mental impairment, with AN IQ below eighty within the majority. Nursing and Health Care is an open access journal with rapid publication process, high quality manuscripts with innovative research which covers all the aspects of Nursing and Health Care.