Donohue syndrome
Donohue syndrome also known as leprechaunism is rare and severe genetic disorder. Leprechaunism is a congenital condition characterized by extreme insulin resistance, pre- and postnatal growth delays, characteristic facial features, skin abnormalities, muscular hypotrophy and enlarged external genitalia in both males and females. The condition is caused by mutations in the insulin receptor gene (INSR) gene. It is inherited in an autosomal recessive manner
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