Drug metabolism is the process by which the body breaks down and converts medication into active chemical substances. Drug can be metabolized by reduction, oxidation, hydration, conjugation, hydrolysis and condensation. The main goal of drug is to eliminate from the body easily. The metabolism differs from person to person, genetic factors influence the rate of the drug metabolism individually.
There are two phases of drug metabolism.
- Phase I: Non-synthetic reactions such as cleavage
- Phase II: Synthetic reactions such as conjugation with an endogenous substance
The drug which is formed in Phase II by synthetic reactions is more polar, and can be excreted in the urine more easily. Pharmacovigilance Journal discusses the latest research innovations and important developments in this field. Pharmacovigilance Journal is interested in the special fields related to the topics of this Journal. Pharmacovigilance and Pharmacoepidemiology Journal offer a stage in Pharmacoepidemiology Researches and related subjects. Journal accepts leading forefront original research papers, review manuscripts, case reports and commentary in the field. Our target audience, readers and contributors are worldwide.