Antibiotic prophylaxis refers to, for humans, the prevention of infection complications using antimicrobial therapy. Antibiotic prophylaxis is most commonly used prior to dental surgery or medical surgery, however, may be used in other cases, such prior to sexual intercourse for patients who suffer from recurrent urinary tract infections. Even when sterile techniques are adhered to, surgical procedures can introduce bacteria and other microbes in the blood, which can colonize and infect different parts of the body. An estimated 5 to 10 percent of hospitalized patients undergoing otolaryngology surgery acquire a nosocomial infection, which adds a substantial cost and an average of 4 extra days to the hospital stay. The journal of Pharmacovigilance and Pharmacoepidemiology aim is to publish high quality research in the discipline of Pharmacovigilance by providing encouragement for editors, reviewers, authors, and readers to have an uninterrupted scientific communication.