A missed dose or incorrectly timed dose of an anticonvulsant may be responsible for a breakthrough seizure, even if the person often missed doses in the past, and has not had a seizure as a result. Missed doses are one of the most common reasons for a breakthrough seizure. A single missed dose is capable of triggering a seizure in some patients. Some medicinal and recreational drugs can dose-dependently precipitate seizures in withdrawal, especially when withdrawing from high doses and chronic use. Pharmacoepidemiology Researches invites an article to publish in the Journal of Pharmacovigilance and Pharmacoepidemiology. Pharmacovigilance and Pharmacoepidemiology is a scholarly journal maintaining high standards of Pharmacoepidemiology Researches.