Delayed drug effects
Delayed drug effects are the Drug effects are delayed in relation to observed drug concentration. All drug effects are delayed in relation to plasma drug concentrations. There are several mechanisms which can explain delayed effects:
- Distribution to the receptor site
- Binding to and unbinding from receptors
- Turnover of a physiological mediator of the effect.
It takes time for drug to distribute to the site of action. After reaching the receptor the process of binding to the receptor may be slow and contribute to delay in response. Pharmacovigilance and Pharmacoepidemiology Journal offer a stage in Pharmacoepidemiology Researches and related subjects. Journal accepts leading forefront original research papers, review manuscripts, case reports and commentary in the field.