Pathophysiology or physiopathology could be a convergence of pathology with physiology. Pathology is that the medical discipline that describes conditions generally determined throughout a disease state, whereas physiology is that the biological discipline that describes processes or mechanisms operative among associate degree organism. Pathology describes the abnormal or unsought condition, whereas pathophysiology seeks to elucidate the practical changes that square measure occurring among a personal because of a disease or pathologic state. Pathophysiology can even mean the practical changes related to or ensuing from disease or injury. Another definition is that the practical changes that accompany a specific malady. Pathophysiology involves either plant tissue or neural structure pathology, as established with neurophysiologic and imaging studies. Rasmussens syndrome is associate degree autoimmune disorder involving one hemisphere, with plant tissue inflammation and atrophy, and so this can be a secondary muscle spasm. Pathophysiology is unknown. Despite the identification of antiglutamate receptor antibodies in some kids, immune-modulating therapies dont have long-run profit and solely hemispherectomy is curative. Pharmacovigilance and Pharmacoepidemiology journal accepts articles from different disciplines as below but not constrained to only these Pharmacovigilance signal, Pharmacovigilance data management, Design and development of drug, Principles of pharmacology, Quality system and pharmacovigilance, Pharmacovigilance softwares, Drug regulatory activities, Drug reactions and diagnosis, Reporting systems, Clinical trials and pharmacovigilance, Marketing surveillance, Pharmacovigilance ethics and regulations, Biomarkers and pharmacology , Concepts and trends in pharmacovigilance, Pharmaceutical medicines, Drug delivery systems, Statistics and data management.