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Edelweiss: Psychiatry Open Access (ISSN 2638-8073)

Volume 5 Issue 1

Research Article

DOI Number: https://doi.org/10.33805/2638-8073.131

Genomic Architecture Differences at the HTT Locus Associated with Symptomatic and Pre-Symptomatic Cases of Huntington’s Disease in a Pilot Study

Matthew Salter, Ryan Powell, Jennifer Back, Francis Grand, Christina Koutsothanasi, Jayne Green, Ewan Hunter, Aroul Ramadass, Jurjen Westra, Alexandre Akoulitchev

Abstract

Introduction Huntington’s Disease (HD) is a neurodegenerative condition characterized cellularly by the loss of neurons in the basal ganglia and clinically by uncontrolled movements, emotional problems, and loss of cognition [1]. HD is an autosomal dominantly inherited disorder and although prevalence rates range widely depending on geo View more

Abstract

Introduction For decades, behavioral science, psychology and psychiatry have been more important in social circumstances [1]. One reason includes increased stress, which may influence the personality of the people [2]. Consequently, some perspective would be required in the light of communication, Transactional Analysis (TA), ego, egogram View more