Edelweiss Journal of Genetics
Edelweiss Journal of Genetics is an open access, peer reviewed journal in Edelweiss Publications, Inc. This journal provides a platform for scientists and researchers all over the world to promote in better scientific way to discuss new issues and developments in different fields of Genetics.
Branches of Genetics which we covers includes Behavioral genetics, Classical genetics, Developmental genetics, Conservation genetics, Ecological genetics, Evolutionary genetics, Genetic engineering, Human genetics, Human evolutionary genetics, Human mitochondrial genetics, Medical genetics, Microbial genetics, Molecular genetics, Population genetics, Plant genetics, Psychiatric genetics, Quantitative genetics, Statistical genetics and many more.
Edelweiss Journal of Genetics publishes articles related to above but not limited to it. All the articles related to Genetics are published online and will be available to the readers worldwide without any Subscription Charge. Edelweiss Journal of Genetics maintained by Edelweiss publications, which ensures of Rapid Peer review with the help of its Editorial Board.
Edelweiss Journal of Genetics welcome submissions related to Genetics. Authors may submit their valuable work at: email@example.com
The scope of Genetics Journal
Edelweiss Journal of Genetics is a peer reviewed journal, with rapid publication process. Genetics is the branch of biology that deals with genes, variations and heredity among the same or related organisms. Mutations, genes, codons, chromosomes, nucleotide, genetic code and allele all this comes under genetics. Gregor Mendel is the father of genetics, who worked with the seven characteristics of pea plants like flower position and color, plant height, seed shape and color, pod shape and color. Genetics helps in many different fields of testing which includes diagnostic genetic testing, Presymptomatic genetic testing, Predictive genetic testing, Carrier testing, prenatal diagnosis, Newborn screening, Preimplantation studies. Edelweiss Publications publishes all articles related to Genetics.
Edelweiss Journal of Genetics welcomes manuscript related to Human genetics. Human genetics is the study of inherited variations occurs in human beings. In simple terms, Human genetics is the study of the human genome and how genes are transmitted through generations. It is the study of the inheritance of characteristics by children from parents. Human genetic research helps to study about susceptibility to diseases of particular individual and hence reveal the information about the individuals future health. It generates knowledge with the potential to improve individual and community health. In human genetics, various fields are included namely known as cytogenetic, classical genetics, biochemical genetics, molecular genetics, genomics, developmental genetics, population genetics, clinical genetics, and genetic counseling. The study of human heredity plays an important role in genetics. Much of this interest has desire to know who humans are and why they are as they are. Practically, understanding of human heredity plays an important role in diagnosis, prediction, treatment of diseases that have a genetic component. Determining the genetic basis of human health has given rise to medical genetics. In general, the terms medical genetics and human genetics are often considered synonymous because medicine has given focus and purpose to human genetics. Advances in human genetics like sequencing of the human genome, have greatly increased the power of both gene discovery and diagnosis and treatment of both rare and common diseases. Edelweiss Publications Inc is a USA based publishes all article related to Human genetics.
Edelweiss Journal of Genetics covers broad scope of topics including Plant genetics. Plant genetics is the study of genes and genetic variation in Plants. It is generally considered a field of biology and botany, but this frequently intersects with many other life sciences. Plant genetics is similar to animal genetics but differs in a few key areas. Discoverer of genetics was late Gregor Mendel; he is a scientist and Augustinian friar. Mendel studied "trait inheritance" how these traits are passed on from parents to offspring.
Plants pass on their traits using DNA; these are unique from other living organisms and consist of Chloroplasts with their own DNA. Plants also experience somatic mutations regularly like animals but these mutations can contribute to the germ line with ease, in plants flowers develop at the ends of branches composed of somatic cells. Mutant branches are called "sports". A sport with a fruit is economically desirable then a new cultivar can be obtained. Some plant species are capable of self-fertilization and some other plants are nearly exclusively self-fertilizers. This means that a plant can be both mother and father to its offspring, a rare occurrence in animals. Edelweiss Publications publishes all articles related to Plant genetics.
Edelweiss Journal of Genetics welcomes all the articles related to basic science for global readers. Gene therapy is an experimental technique that uses genetic material into cells to treat/prevent disease or a DNA is introduced into a patient to treat a genetic disease instead of using drugs or surgery. A gene is delivered into cell by using a carrier called vector because the gene cannot be directly inserted into a cell, as it does not function. They are two types of Gene therapy known as namely:
· Somatic gene therapy: Transfer of therapeutic DNA into any cell of the body which does not produce sperm or eggs.
· Germline gene therapy: Transfer of DNA to cells that produce eggs or sperm, these gamete cells fuse to form a zygote and which divide and pass on the modified gene into other cells of the body during the development of offspring.
The possibilities of treating certain diseases by using gene therapy are monogenic disorders (single gene is used which is responsible to treat the disease) like sickle cell anemia, severe combined immunodeficiency, cystic fibrosis, hemophilia, Duchene muscular dystrophy, Huntingtons disease, Parkinsons, hypercholesterolemia, Alpha-1 antitrypsin, chronic granulomatous disease, Fanconi Anemia and Gaucher Disease. Polygenic disorders (multiple genes involved to treat diseases) like Heart disease, Cancer, Diabetes, Schizophrenia and Alzheimers disease and infectious diseases such as HIV. Edelweiss Journal of Genetics is an open access maintaining high standard quality articles of basic science.
Edelweiss Journal of Genetics is interested in the special fields related to the topics of Genome biology. A genome is the genetic material of an organism and is the branch of genetics and molecular biology. It is a complete set of DNA which includes all set of genes of an organism. The study of the genome is called genomics. Genome consists of RNA or DNA in RNA viruses. The coding DNA, noncoding DNA, mitochondrial DNA and as well as chloroplast DNA are included in the genome. The nucleotides A, C, G, and T for DNA genomes is a genome sequence which make up all the chromosomes of an individual or a species. Within a species, the majority of nucleotides are similar between individuals but to understand the genetic diversity sequencing multiple individuals is necessary. The order of every DNA based in genome is listed in a genome sequence; a genome map identifies the landmarks. A genome map is less detailed compared to genome sequence and helps in navigating around the genome. To map and to sequence the human genome the Human Genome Project was organized. The development of new technologies has made genome sequencing dramatically easier, and the number of complete genome sequences is growing rapidly. Edelweiss Publications has a rapid review process, it tries to publish the manuscript within 4-6 weeks of time after submission.
Edelweiss Journal of Genetics covers the area of Medical Genetics to publish articles in our journal. Medical Genetics is the branch of medicine that helps in finding of hereditary disorders. For instance, research on the causes and legacy of genetic disorders would be considered inside both human genetics and medicinal genetics, while the determining and advising individuals with hereditary disarranges would be viewed as a feature of therapeutic genetics. In differentiate; the investigation of ordinarily non-restorative phenotypes, for example, the genetics of eye shading would be viewed as a major aspect of human genetics, however not really significant to medicinal genetics. Genetic medicine is mostly used in therapeutic genetics which helps in customized drug, quality treatment, prescient medicine and the quickly developing new restorative claim to fame. Precedents of conditions that fall inside the extent of medicinal genetics incorporate birth abandons and dysmorphology, mental impediment, chemical imbalance, mitochondrial disarrangements, skeletal dysplasia, connective tissue issue, malignant growth genetics, teratogens, and pre-birth conclusion. Edelweiss Publications, Inc. the review process is done by their active editorial board members only, which help in reducing the timeline for publishing the manuscript after submission.
Edelweiss Journal of Genetics running by Edelweiss publications accepts all types of articles related to DNA replication. DNA replication is meant for biological inheritance, the DNA replication is helpful in molecular biology in the procedure of producing two identical replicas of DNA from one unique DNA molecule. The cell has the specific property of division, which makes replication of DNA essential. DNA is comprised of a twofold helix of two integral strands. During replication, these strands are isolated. Each strand of the DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. Because of semi-conservative replication, the new helix will be made out of an original DNA strand as well as newly synthesized DNA strand. Cellular proof reading and error checking components mechanisms ensure near perfect fidelity for DNA replication. In a cell, DNA replication starts at particular areas or origins of replication in the genome. Unwinding of DNA at the origin and synthesis of new strands, accommodated by an enzyme known as helicase, results in replication forks developing bi-directionally from the birthplace. Various proteins are related with the replication fork to help in the initiation and continuation of DNA synthesis. Most remarkably, DNA polymerase synthesizes the new strands by including nucleotides that complement every strand. DNA replication happens during the S-phase of interphase. Edelweiss Publications encourage students and researcher to submit their valuable research in their Journal of Genetics.
Edelweiss Journal of Genetics covers broad scope of topics including Genetic code. Genetic code which carries genetic information by the set of rules utilized by living cells to convert into proteins (DNA or mRNA groupings are used are genetic transformers). Translation is accomplished by the ribosome, which joins amino acids as indicated by messenger RNA (mRNA), utilizing transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at any given moment. The genetic code is highly similar among all life forms and can be communicated in a straight forward table with 64 entries. The code characterizes how successions of nucleotide triplets called codons determine which amino acid will be included next during protein synthesis. With some exceptions a three-nucleotide codon in a nucleic acid succession determines a single amino acid. By far most of genes are encoded with a single scheme. That scheme is often referred to standard genetic code though variant codes (which is similar to human mitochondria). While the "genetic code" decides a proteins amino acid succession, other genomic areas decide when and where these proteins are produced by different "gene regulatory codes". Edelweiss publications emphasize in publishing the original scholarly articles related to Genetic code worldwide. The journal follows rapid review process with the Eminent Editorial Board.
Edelweiss Journal of Genetics accepts original Research Articles, Review Articles, Case Reports, Mini Reviews, Rapid Communication, Opinions and Editorials on all the topics of Genetics and Mutations. Mutation is defined as a change in nucleotide sequence due to errors of DNA replication, recombination, chemical mutagens and viruses/transposons. Mutations may likewise result from insertion or deletion of portions of DNA because of mobile genetic elements. Mutations could possibly deliver noticeable changes in the detectable attributes (phenotype) of a living being. Mutations have impact in both normal and abnormal natural procedures which includes malignant growth, evolution and in improvement of the immune system. The genomes of RNA infections depend on RNA instead of DNA. The RNA viral genome can be twofold stranded (as in DNA) or single stranded. In a portion of these infections, (for example, the single stranded Human Immunodeficiency Virus) replication occurs rapidly and there are no mechanisms to check the genome for precision. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as, DNA repair to avoid or correct mutations by reverting the mutated sequence back to its original state. Edelweiss Publications, is a scholarly journal maintaining high standard articles of Mutations.
Edelweiss Journal of Genetics is committed to publish top-tier original research in all areas of Genetics and related fields through a fair and rigorous review process. Genetic marker is defined as a gene or DNA sequence with a known location on a chromosome which helps to identify individuals or species. It can be called as a variation which arises due to mutation or alteration in the genomic loci that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites. Relationship between an inherited disease and its genetic cause can be studied with the help of genetic markers. Genetic markers should be easily identifiable with a specific locus and are highly polymorphic because homozygote does not provide any kind information. But by using RNA sequencing or indirect using allozymes markers can be detected directly.
Types of genetic markers which are used commonly are:
· Restriction Fragment Length Polymorphism (RFLP)
· Simple Sequence Length Polymorphism (SSLP)
· Amplified Fragment Length Polymorphism (AFLP)
· Random Amplification Of Polymorphic DNA (RAPD)
· Variable Number Tandem Repeat (VNTR)
· SSR Microsatellite Polymorphism, (Simple sequence repeat)
· Single Nucleotide Polymorphism (SNP)
· Short Tandem Repeat (STR)
· Single Feature Polymorphism (SFP)
· Diversity Arrays Technology (DArT)
· Restriction site associated DNA markers (RAD markers)
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