Health Care Journals | Open Access - Edelweiss | Edelweiss Publications

Journal of Obesity and Diabetes (ISSN: 2638-812X)

Keywords

Leptin receptor

Leptin receptor also known as LEP-R/OB-R is a Type I cytokine receptor encoded by the LEPR gene humans. LEP-R functions as a receptor for hormone leptin regulates adipose-tissue mass. Leptin receptor deficiency is a condition that causes severe obesity. The extreme hunger leads to hyperphagia and obesity. People with leptin receptor deficiency also have hypogonadotropic hypogonadism.

Leptin receptor deficiency is caused by mutations in the LEPR gene. This condition is inherited in an autosomal recessive pattern.
The db/db mouse is a model of obesity, diabetes, and dyslipidemia wherein leptin receptor activity is deficient because the mice are homozygous for a point mutation in the gene for the leptin receptor

Journal of Obesity and Diabetes emphasize in publishing the original scholarly articles related to Obesity and Diabetes worldwide. The journal follows rapid review process with the Eminent Editorial Board

Editorial Board

Jhon Smith

Professor

editor
Jhon Smith

Professor

editor
Jhon Smith

Professor

editor
Jhon Smith

Professor

editor