Islet of Langerhan
An islet of Langerhan is an irregular shape patches of endocrine tissue located within the pancreas. The pancreas contains clusters of cells that produce hormones. These clusters are known as islets. The islets consist of cell types like alpha, beta, and delta cells. The most common islet cell is the beta cell which produces insulin, and so play a significant role in diabetes. The beta cell also helps in the regulation of carbohydrate, fat, and protein metabolism. Insulin is crucial in several metabolic processes: it promotes the uptake and metabolism of glucose by the body cells; it prevents release of glucose by the liver; it causes muscle cells to take up amino acids, the basic components of protein; and it inhibits the breakdown and release of fats. The inability of the islet cells to make insulin or the failure to produce amount sufficient to control blood glucose level are the causes of diabetes mellitus
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