Plasminogen Activators are heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. Plasminogen activators are serine proteases that catalyze the activation of plasmin. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. Urokinase (uPA) and tissue plasminogen activator are the two main plasminogen activators. Plasminogen Activators are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation. Plasminogen activators are inhibited by plasminogen activator inhibitor-1, plasminogen activator inhibitor-2, and protein C inhibitor. Edelweiss Publications accepts all the articles related to computer science and benefit the authors with more citation and global readers. Edelweiss Applied science and technology journal is a platform for authors to submit their valuable research work of material science and get global readers.