Pharmacodynamics is the study of the biochemical, physiologic, and molecular effects of drugs on the body. In simple terms, it describes what a drug does to the body. Pharmacodynamics emphasizes the relationships between drug concentration and its effect. Animal models in the pharmacodynamics evaluation play a significantly important role in preclinical assessments of new agents, dosing optimization for those that are clinically approved, and setting or confirming susceptibility breakpoints.
A drugs pharmacodynamics can be affected by physiologic changes due to
· A disorder
· Other drugs
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