Bone to death due to loss of blood flow to bone tissue is known as osteonecrosis. Hip, knees, shoulders, and ankles are mostly affected by this disease. Serious trauma, consuming high dosage of corticosteroid medications like prednisone, cortisone or methylprednisolone, excess alcohol consumption, systemic lupus erythematosus are causes of osteonecrosis. Pain, redness of the skin, swelling, blisters, fluid collection, skin discolouration, sensation and numbness are some common symptoms of the disease.
Chemical changes in the bone marrow in the earliest stages can show osteonecrosis; this can be diagnosed by MRI. Pain medications, limiting weight-bearing and surgery are treatments for osteonecrosis. Nonsteroidal Anti-Inflammatory Drugs or NSAIDs are used in the treatment of osteonecrosis by reducing inflammation in the soft tissues surrounding the joint. Stomach upset, ulcers and side effects may affect due to long term usage of NSAIDs.
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