Journal of Heterocyclics (ISSN 2639-6734)

Research Article :

Cefuroxime Axetil: A Commercially Available Pro-Drug as Corrosion Inhibitor for Aluminum in Hydrochloric Acid Solution

Paul O Ameh and Umar M. Sani


Cefuroxime axetil (CA) a pro-drug was tested as corrosion inhibitor for aluminum
in hydrochloric acid solution using thermometric, gasometric weight loss and scanning
electron microscope (SEM) techniques. Results obtained showed that this compound
has good inhibiting properties for aluminum corrosion in acidic medium, with inhibition
efficiencies values reaching 89.87 % at 0.5 g / L. It was also found out that the results
from weight loss method are highly consistent with those obtained by hydrogen evolution
method and gasometric method; and all indicate that inhibitor efficiency increases with
increasing inhibitor concentration. Cefuroxime axetil inhibited the corrosion of aluminum
in solutions of HCl through the mechanism of physiosorption as confirmed by values of
activation energy and free energy of adsorption. The adsorption of the inhibitor was also
found to be spontaneous, exothermic and best fitted the Langmuir adsorption model.
SEM analysis confirmed the existence of an absorbed protective film on the aluminum



Adsorption; Aluminium; Corrosion Inhibition; Cefuroxime axetil; SEM



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