Heart failure is among the most prevalent chronic condition in older adults  and hospitalizations account for the majority of costs related to treatment of heart failure . Self-management is the primary key to control symptoms, disease progression and improve health outcomes. Studies have reported the low self-management adherence to heart failure treatment guidelines and its health consequences. Persistently high mortality and readmission rates in rural heart failure patients indicate a need for developing interventions to improve self-management adherence. Effective approaches to support heart failure patients in managing this complex, chronic condition in rural communities have not been reported . To fill the gap of knowledge and evidence regarding interventions intended to improve self-management adherence in rural heart failure patients, a two-group, Randomized Control Trial (RCT) was conducted to examine the feasibility and impact of a two-phase, 12-week intervention on patient knowledge and confidence in managing their heart failure a rural community. It was hypothesized that enhanced patient knowledge and confidence would improve activation levels, leading to improved heart failure self-management adherence. The intervention combined inpatient discharge planning with home-based self- management coaching. To evaluate the effectiveness of the intervention on self- management adherence, the on-going assessments were conducted at baseline (before the onset of intervention), 3- and 6-months after the intervention. Both objective (assessed by Actigraph monitor) and subjective data (assessed by questionnaires) were collected at each time point.
The conduct of behavioral RCT in rural comminutes can be challenging, particularly regarding to patient recruitment and retention. It is not uncommon for investigators to be unable to meet recruitment goals within the proposed timeframe [4,5].To detect the statistical significant differences between intervention and control groups, adequate sample size of rural residents are needed . Therefore, low enrollment and high attrition rates would hinder the development of effective strategies to improved self- management adherence in rural heart failure patients. Moreover, inadequate sample size would limit the validity and generalizability of study results to heart failure population residing in other rural and remote areas. To date, limited studies [7,8] reported barriers and strategies to improve recruitment and retention of rural participants in research studies. The purpose of this paper is to descript the experience and lessons we learned when conducting a RCT in the rural community: the barriers and strategies related to recruitment and retention of rural heart failure patients in a behavioral intervention study to improve activation level and self- management adherence. The study was approved by the University of Nebraska Medical Center Institutional Review Board (IRB) and hospital ethical committees, receiving the number of IRB PROTOCOL # 228-13-EP. All patients gave written informed consent for participation in the study. The study was registered at https://www.clinicaltrials.gov/ct2/show/NCT01964053.
This is a retrospective and descriptive design.
Data Collection Process
Enrollment and recruitment started in October 2013. Heart failure patients admitted to a rural community hospital in Southeastern Nebraska were first screened for eligibility based on the inclusion/exclusion criteria, then the eligible patients were approached and asked whether they were interested in participating in the program. The author was the nursing staff at the community hospital and had full access to the targeted population. The author was responsible for the recruitment and enrollment of the study subjects. She visited the hospital on a regular daily basis, reviewed the patients records, checked the floor daily census, and interviewed the hospital staff (e.g., nursing staff, medical providers, housekeeping, unit secretaries, house supervisors) to identify potential study subjects. The author administrated two screen tools to the patients who met the inclusion criteria. The two screen tools were used to detect the impaired cognition level and depression. Following the screenings, the author approached each the patient who passed the screenings and met the inclusion criteria. She asked if the patient was interested in participating the study. The author made field notes detailing the reasons that patients declined to participate the study.
After explaining to the patients and their family members the purpose, outcomes, procedure, and the risks and benefits of the program, the author addressed any questions or concerns about the consent and the study. The patients were provided ample time to review the consent form and the study protocol prior to signing the consent. The author also kept records on the rationale for deciding to exclude patients who passed the initial screenings and met the inclusion criteria at the final stage of enrollment. Following the informed consent, the enrolled patients were randomized to either the intervention or control group. Baseline data were collected and the patients in the intervention group received Phase I of the intervention during their hospital stay. Within a week of discharge, reminder calls were made by the research assistant to reinforce the purpose, risks and benefits of the study, address any questions and concerns raised by the patients, and remind the patients to wear the Actigraph monitors (physical activity assessment tool) based on the study protocol. Prior to the 3- and 6-month data collection, the participants from both groups received reminder letters about the upcoming phone interviews from the research assistant, blood and urine collections and Actigraph monitoring. The research assistant made additional phone calls to remind the patients who failed to return the blood and urine samples and Actigraph monitors. Thank you letters were sent to those who completed the data collections. An incentive of $50 was sent to those who completed all three data collections.
The author kept records during the recruitment, enrollment and follow-up process including the demographic data of each patient reviewed for the study (e.g., age, gender, marital, working status), eligibility for the study (met or not met the inclusion criteria), screening results (passed or failed the two screening tools), consent status (agree/decline to consent to be the participant), reasons for declining, reasons for excluding following the initial screening, dropout time and the reasons for dropout. Both quantitative and qualitative methods were used to describe patients who chose to enroll or ot enroll the study. This mixed method analysis helped us to capture a broad range of challenges and opportunities in conducting rural research. For the quantitative approach, the descriptive statistics (counts, mean, standard deviation, median, percentage) were used to describe the normally distributed continuous variables. The median and range were used to describe non-normally distributed continuous data. Frequency and percentage were used to describe categorical variables. A t-test for two independent samples was used to compare the normally distributed continuous variables between the enrollers and non-enrollers. The Mann Whitney U Test was used to compare the variables whose normality cannot be assumed. The information related to the barriers and effective strategies to recruit and retain the participants were collected from the authors field notes, the written reports from the research assistants. The qualitative data were grouped into several categories to organize the information and develop solutions. The quantitative and qualitative data were collected and analyzed independently and then the findings were merged to help develop interpretation of the results.
Since October 14, 2013, A total of 589 potential candidates were screened, the reasons for screen failure include: 1) failed inclusion/exclusion criteria; 2) declined to participate; 3) transferred to another facility; 4) deteriorating health condition; and 5) time restrictions. Among 85 subjects, one dropped out after consent, one dropped out at baseline and one subject expired. Table 1 listed subjects demographic characteristics. The mean age is 70 ± 12.3 years. There are more women (66%) than men (34%) in this study. The majority are white (97.6%) and not working (69%). Sixty-two percent of subjects had annual household income below $30,000 ( Table 1 ).
Comparing the enrollers to non-enrollers, the enrollers were older, female, had lower co-morbidity level, higher physical functioning, higher patient activation level, a more positive attitude and outlook, higher health literacy, and better self-management knowledge, skills and adherence. The non-enrollers were often male, had more complex chronic conditions with poor prognosis, were weaker due to progressive physical and psychological deconditioning, and were receiving multiple treatments for multiple comorbidities. Barriers and challenges to participating research Reasons for the decline of participation are listed in Figure 1. Research related barriers to participating in research Inability to perceive the study benefits: Inability to perceive the study benefits was one of the most frequently cited reasons for not participating. Many patients refused to participate because they did not perceive the benefit or need to be in the study. A patient expressed, “I know....I know....you try to get me do this study so I can be the guinea pig for others.....Nope, I need get something out of this too, not just sacrifice....” Many other patients shared similar feelings and thoughts. Some patients request the personal assistance with their activities of routine daily living (e.g., bathing, cooking, shopping, and refilling the pill box). Others preferred the intervention delivered through face-to-face format with more hands-on coaching. One patient said, for example: “I know all the things I need to do to keep me out of trouble, but I dont know how. I need someone to come to my house to show me how to cook meals to keep under 1500mg sodium a day, how to cut down the fluids.” Similarly, another patient did not think this intervention would provide the on-going support he needed to consistently engage in the self-management behaviors. He said, “I knew why I am [in the hospital] again, I was not taking the pill I was supposed to and eating a lot of salty food, I know everything you are going to lecture to me, my problem is...I am not doing what I am supposed to do....I can be good for a week, then fall off wagon....I dont think your program can help me ....I dont need a lecture anymore...I need someone come to my house, physically check on me all the time.” However, others felt they were getting adequate care from their current providers and support system, and therefore did not perceive the need for additional support.
During the intervention sessions, some participants questioned the benefits of following heart failure self-management guidelines. One said, “Sure, [the interventionist] told me to keep the scheduled follow-up appointment, yes, I went to the scheduled doctor appointment. I live on the ranch, it took me one hour to get to town and one hour to get back home, then I waited in the waiting room for almost an hour, then another 30 minutes in the exam room, guess what?! He spent no more than 5 minutes with me, he did not even know I was in hospital because he did not get the letter from the hospital. You are telling me that was a helpful appointment to me?!” Some participants voiced their doubts about the unrealistic expectations of the self-management guidelines for heart failure patients. One remarked, “You ask me to eat only one and one half teaspoons of salt a day, everything has salt in it, even vegetables, I have to be a vegan to meet your requirement. Those pills I take make me thirsty and tired all the time, how would you expect me not to drink when the doctor prescribed the pill making me thirsty? How would you expect me to exercise 30 minutes a day when the pill makes me tired all the time?” Some participants dropped out because they were unable to meet the self-management guidelines and disbelieved the benefits of self-management guidelines.
Research Related Factors
• Inability to perceive the study
• Perceived research burden and life interruptions,
• Lack of understanding or misunderstanding the research
• Mistrust Health Related Factors
• Muttiple cornorbidities
• Negative feelings and outlook
• Low health literacy Personal Factors
• Reluctant to engage in self-management behaviors
• Lack of resources and support
• Multiple demands in life
Figure 1: Reasons to Refuse Participating in the Research
Perceived research burden and life interruptions
Study burden and interruption to life were another reason for declining that was repeatedly brought up by the patients. Many patients were discouraged by wearing the activity monitor at least 8 hours per day for 7 days. Some felt that the weekly calls from the interventionist were burdensome and disrupted their routines. Some patients expressed that it was “ too much work for driving into the town for blood work ”. Several patients were not aware of the rationale behind longitudinal studies. They expressed disappointment about the 6-month follow up data collection and felt “being watched for 6 months” was lengthy and burdensome. Lack of understanding or misunderstanding the research Many research participation due to a lack of understanding and misunderstood the research with respect to its purpose, process, procedures and outcomes. One patient said, “ My daughter did not want me join your program. She said your study does nothing but the experiments on me .” Another patient said, “I just dont get it [the research project] what you are trying to do.....give me money to take care of me??!!....Are you crazy?!” Some felt intimidated by signing the consent. Another patient commented , “Why do I have to sign this 9-page long paper? Are you going to take away my house if I am not doing this right?” A patient refused to participate after we requested her social security number for the incentive check. Ignorance and lack of understanding about the benefits of research affected patients participation rate.
Some patients refused to participate in the study because they considered the researchers as “ outsiders ” to the community or “ people working for the government ”. One patient asked if the study was “another gimmick the government comes up to get people”. Some patients expressed difficulty in trusting someone they did not know. One commented, “ What do you know about me and my problem? You have to understand it is very hard for me to join your program if we have never met before .” Many patients voiced their “ die hard loyalty ” to their primary providers; thought participating the program would jeopardize their relationship with the physicians. One remarked, “I have been going to my family doc for years, he knows my problems well, I dont want to upset him by going to someone else.” Many patients, especially older ones, asked if their family doctors were aware of the study and refused to participate the study without the “ ok letter ” from their family doctors.
Health related barriers to participating in research Multiple comorbidities
Most potential candidates had multiple chronic conditions. They refused to participate in the study because they felt overwhelmed and exhausted from managing their multiple health problems. One patient said, “My health problems are taking my life away, sucking my energy dry, I am too tired to do anything, honey.” Another patient was “ burned out ” by managing his chronic conditions: “I have 12 doctors taking care of my health problems, I go to doctors offices and hospitals every 2-3 weeks, sometimes, every week, I am tired to being old, I am tired of being sick all the time, to be honest with you, I am tired of seeing your guys, sorry.”
During intervention sessions, some participants wished to receive integrated self-management information that would help them manage multiple chronic conditions rather than heart failure only. For example, one participant was confused by the conflicting care instructions for different diseases she had, explaining, “My rheumatologist told me to drink a lot of water because he put me on this new pill causing the kidney stone, but my heart doctor and you told me to drink less because my heart is failing. You guys are teaching conflicting things. What am I supposed to do?” Another participant had multiple chronic conditions, heart failure, diabetes, osteoarthritis, and he had difficulty meeting heart failure self-management guidelines due to the interference from his other conditions. He expressed his frustration to the interventionist: “It was difficult for me to exercise 30 minutes a day, I even tried to break it down to small sessions like 10 minutes in the morning, 10 minutes in the afternoon, and 10 minutes at night. I did for 2 days in a row, then my arthritis all flared up. I have the lower spine stenosis and my back was killing me after the walking the other day, not to mention the blisters on the bottom of my feet... I have had diabetes for years and my feet dont have much sensation.” Several patients conditions progressively deteriorated during the hospital stay and they became dependent in activities of daily living due to the complex comorbidities. As a result, the author excluded these patients from the study although they met the inclusion criteria and passed the initial screening. The author did not think this self-management program would be a good fit for those who were incapable of caring for themselves.
Negative feelings and outlook
Several patients expressed feelings of guilt and shame regarding their current health conditions. One said, “I was not willing to change my life when I had chance....now it is too late.” Some participants admitted that participating in the study made them feel depressed and angry towards themselves: “Doing this study makes me realize how bad a shape I am in, how terrible a life I have lived, I am on 30+ pills a day, see doctors every month, and it takes me 3 rests to get to the mailbox. Damages done when I was young and I dont see the future”.
Low health literacy
Several patients who passed the cognition screening tools had difficulty in comprehending the information related to heart failure self-management knowledge. Some patients lacked understanding about the chronic nature of heart failure. One heart failure patient said, “I dont have heart failure anymore and I was cured by a cardiologist a couple years ago.” Another patient was diagnosed with congestive heart failure three years ago following her coronary artery bypass surgery. He was surprised to know he has had this condition, stating, “Heart failure? I dont have [heart failure], no one told me before.”
Personal barriers to participating in research
Reluctance to engage in self-management behaviors
Some patients refused to participate in the study because they were unwilling to engage in self-management behaviors. Some had no motivation or desire to take responsibility in managing their condition. One said, “My family doctor and the specialists take care of me if I am sick. They know more than I do, let them worry about [heart failure].” Another remarked , “It is not my job to manage my heart problems. I paid doctors to take care of me”.
Rural patients living on farms and ranches were reluctant to travel long distances for lab testing. Some elderly patient with degenerative joint diseases and arthritis expressed difficulty in walking from the parking lot to the hospital building. A patient said, “that damn parking lot is 2 miles away from the building, too much walking; I am not coming for the blood work.” Some lost their ability to drive and did not want to spend money for transportation for the lab work. Several candidates were “snowbirds” who moved to the warmer southern states in winter months. Lack of resources and support Rural patients living in poverty were likely to refuse to participate in the study because of a lack of funds to pay for transportation and telephone services. Two patients were homeless and were discharged and transported to the homeless shelter by the police. Several patients did not join the program because of a lack of family support and approval. A patient told the author, “honey, Id love to join the program, but my daughter said no.” Later on, the patient was moved to an assistant living facility from her home following the disclosure of domestic abuse.
Multiple demands in life
Some potential candidates were still working on farms, working outside of the home, traveling frequently, engaging in busy social lives, or acting as caretakers of family members. They declined the study because of multiple competing life demands.
Strategies to Recruitment and Retention
Strategies to improve recruitment and retention to the study are listed in Figure 2 .
Research related factors that promote recruitment and retention
Relationship with the recruiter
Having a recruiter who had an established relationship with the participants and lived in the same community seemed to foster recruitment and retention. The author, who worked as a staff nurse at the study site, was primarily responsible for recruitment and retention. The patients felt more comfortable and relaxed when they found out the lead of the program was a nurse they had known for years. One patient said to the author, “I am doing this just for YOU.” Some patients expressed their trust in the research team member from the local community. One patients said, “I trust you, my family trusts you, and so I will join the program for you”. Another said, “Six months?! Well, I guess I can put up with you for six months.” Some had previous relationships with the recruiter, saying “My wife said I should sign up for this program, you were her nurse years ago, she said you were really good to her” When the author explained the risks and benefits of the study, one patient said, “Yeh, yeh, there is no such thing as risk-free, I just dont believe you would do anything to hurt me, I know where you live, lets just cut to the chase and sign me up!”
The patients who received encouragement from their PCPs were more likely to participate in the study. One patient said, “My family doc said you are doing a study to help people, I will do whatever he says.” Another patient said, “If my doctor says yes, I would do it.” One participant admitted wanting to drop out of the study, but he stayed to the end and completed the study. He disclosed, “If it was up to me, I would have dropped out from this [study] a long time ago. But my family doc said this is good for me and keeps me on the right track.” Another patient who was not hospitalized called the author to ask join the study and was disappointed when the inclusion criteria were explained, claiming, “My family doctor showed me your study advertisement; he gave me your phone number to see if you can sign me up. You dont accept anyone if it is not hospitalized?! That aint right, you should accept anyone who has heart failure.”
Previous research experience
Patients who had previous experience in taking part in research studies were more likely to accept the invitation. One patient said, “I did the breast cancer research several years ago, I know how this works, yes, sign me in.” After she completed the study, she phoned the author and asked to be on the call list for upcoming studies. Desire for research incentives and free lab testing Many patients, especially those with low or no incomes, appreciated the incentives provided at the completion of the study. For some participants, the $50 incentives were significant contributions to their budget for daily living. One participant said, “ I need the money, it will help pay for my next week of groceries.” Some patients were interested in the free lab testing and the other monitoring provided by the study, explaining, “I can only afford free-healthcare, if it is free, I am in.”
Health related factors that promote recruitment and retention Desire and motivation to change
Some patients who were hospitalized due to their exacerbated cardiac condition felt it was time to make changes and focus more on their health. They thought the self-management program would give them a jump start. A farmer said, “I have a lot of health issues, forced me out of farming which I care most and know best (tears coming out his eyes)......I am motivated to change my life so I can farm again.” Some considered the hospitalization to be a wake-up call. One patient said, “My son has not been married, I cannot go now, I need to see him getting married and see my grandson born, I dont want to give up yet, help me.” Another woman with stage III heart failure admitted the fear of death and loss: “My husband and I knew each other since we were kids, but we only have been married for 10 years. I wish we have more years to be together. I dont want to die, he would be lost without me. Can your program help me go in the right direction?”
Previous experience with self-care of chronic disease
Patients who had experience caring for relatives with heart failure or other chronic conditions were more interested in participating the study. One patient said, “My husband died from heart failure, I still kept his weight charts....that was hard....I wish I had known more about [heart failure].....now it is my turn....” Believing in and practicing lifestyle medicine Patients who had higher health literacy and actively engaged in self-management behaviors were more attracted to the study. One patient shared, “I am already doing this stuff on my own [eating a low salt diet, taking pills as prescribed, being active, weighing myself every day, and going to scheduled doctor appointments], I would love to get free support and monitoring from your study.” Another patient subscribed to American Heart Association newsletters and followed the posted heart healthy diet instructions. He testified to the fact that engaging self-management behaviors saved his life: “My doctor told me I had a year to live seven years ago. Now I am still here because I changed the way I used to live...I believe I can live a long, healthy life with heart failure. Id like to sign up for your program.” The participants who benefited from the program were also likely to complete the study. One patient told the interventionist, “I can breathe better, walk steadier, feel more energy after I lost all the water weight now”.
People with healthcare seeking behavior
The patients who had a tendency to frequently utilize healthcare facilities had greater acceptance to the program. One patient who was labelled as a “frequent flyer” by emergency department nurses was enthusiastic to join the study: “I feel better when I am around doctors and nurses because I have so many problems. I went to 42 doctor appointments in the past year, everyone knows me here, Id love to participate in your program.” Personal factors in promoting recruitment and retention Presence of a support system Male patients living with a spouse or a partner were more likely to join and complete the study. Many male patients approached by the author admitted that they would not have participated in this study without their spouses or partners. One patient said, “My wife will cook the low salt food and watch my weight.” When approached by the recruiter, another patient said , “you have to wait for my wife, she is coming, ask her because she will be the one doing this, I will do what she tells me.” Another patient who lived with his girlfriend proudly announced , “ Sure, my friend will drive me here to get lab tests done. ” One male patient admitted, “ My wife and daughter think I should do this .” Some adult children asked the author to enroll their parents to the program: “My mother has bad depression after my dads gone, she pretty much isolated herself from others. We felt like we lost both parents at the same time, she is not herself anymore. This weekly call will help get her out of her depression mood and push her to interact with others again.” Another patients daughter said, “my mother is the only thing God left for me, I am not ready to let her go... ..I know she does not meet your criteria, she is too old and too weak, but please take her, that will make her feel better about herself, I want her around for many more years, call me selfish, I dont care, I want to keep her...”
Positive outlook and attitude
Patients with positive attitudes easily accepted the program. One veteran confessed, “ I know the damage is done when I was young...those drinking and smoking did not do any good on my heart and my veins, but Id like to make changes even though it might be too late .”
Feelings of loneliness
Some Patients participated in the study for companionship. One woman lost her husband four years prior and her children lived out of state. She said, “Honey, no one has talked to me for 6 months, someone will call me every week? I am in.” Another woman completed the study stated, “I felt good when called me regularly; I was expecting her calls when the scheduled time came and talking to her made me feel she truly cares about me.”
Chronic conditions like heart failure not only have a large impact on society as a whole, but also on the quality of life of the patients . The number of rural residents with heart failure and other cardiac conditions is expected to rise rapidly as a result of increasing life expectancy [10,11]. Heart failure patients are more likely to have other chronic conditions [11,12] and these patients are struggling to manage their multiple chronic conditions . Inadequate self-management contributes to high healthcare utilization (hospitalization and Emergency Department visits) and its associated expenses. Eventually, the diseases debilitate the patients capability to live at home independently and result in long-term care placement . Therefore, it is important to promote self-management knowledge and skills in order to prolong independence and reduce the healthcare related burden in an aging society. Identifying and developing effective strategies to support self-management in rural communities requires more rural-based studies to discover and add new evidence. However,
greater challenges in conducting research in rural settings result in the underrepresentation of rural participants in research trials. Studies among rural cardiac patients generally show poor participation rates of 30–50% . Studies have shown that non-participants differ significantly from study participants in terms of personal characteristics, clinical profiles and self- management behaviors. The non-participants were more likely to have low health literacy, inadequate support and resources, lower adherence to self-management guidelines, poor relationships with care providers, complex comorbidities and lower capacity of self- management, leading to higher healthcare utilization and poorer quality of life .
Implication for Developing Research Recruitment and Retention Strategies
Clearly, the relationship between the recruiter and the patient is a key factor in whether or not patients elect to participate in studies. Using a local recruiter who has established relationships with the patients and lives in the same community is an important gateway to successful recruitment and retention in rural research. The PCP can also play a critical role in recruitment and retention. To enhance the PCPs engagement, we sent regular letters to update the PCP on the progress of the program. The on-going and timely communication were maintained with the PCPs by faxing or phoning abnormal lab results and discussing the special cases of high risk subjects (e.g. lack of resources, non-adherence to self-management guidelines, complex disease profiles, and unfavorable family dynamic). The diagnostic testing were performed at the doctors office to save the subjects trips to healthcare settings. The study also helped establish rapport with the PCPs. The PCPs felt more appreciated when they knew what was going on with their patients and were more like to support the research. Some physicians converted from opponents to supporters of the research and referred their patients to the program. One physician said, “I dont feel lonely anymore because, for a long time, I thought I was the only one fighting this forever lost battle [to get the patients to engage and be accountable for their own health], now, we can do this together! ” In addition, the complementary alliance between medical and nursing staff was noted by the PCPs. Generally speaking, patients felt it was easier to share the truth and “naughty thoughts” with the nurses than the physicians. They were more openly to confess their unhealthy habits and non- adherence (e.g., smoking, drinking, skipping pills), and expressed their disagreement with medical advice and health information to nurses than to physicians. With the assistance of nurses, physicians would have more comprehensive knowledge and understanding of patients self-care needs, which is necessary to develop tailored treatment plans to meet individual health needs as well as have a more reliable evaluation of treatment outcomes.
It must be recognized that inherent limitation accompanies this original randomized control trial. First, many heart failure patients would be good candidates for palliative care programs due to their life-limiting advanced illness, complex self-management regimens and disabled self-management capabilities. The current study was not designed to meet the care needs of patients who were no longer capable of caring for themselves. Unfortunately, there is no effective rural community-based, hospital-initiated palliative care program in place at this time. The author felt a strong desire and professional responsibility to identify and develop an effective palliative care program to meet the care needs of such patients to reduce the care burden and relieve the agony of patients and families. Secondly, during the study, the author witnessed how heart failure patients struggled to adhere self-management guidelines in addition to caring for their other chronic conditions. The intervention was specifically designed for patent with heart failure only. In reality, most patients had other aging-induced illnesses (e.g., degenerative joint diseases, pain, neurological disorders). It was impossible and infeasible to exclude patients with multiple chronic conditions. Instead, more generic intervention content should be developed to meet patients needs in managing multiple chronic illnesses. So far, the effectiveness of an intervention including multiple chronic illness management guidelines has not been reported. Lastly, the author felt as though the “wrong” patients were recruited to the study. The patients needed the most help were reluctant to participate due to various challenges. The study was more attractive to those patients who had already actively been involved in lifestyle modification behaviors, who were active learners and seekers of health promotion information, or those who experienced the benefits of self-management outcomes. This selection bias inevitably affected the study results. For instance, if such motivated subjects were randomly assigned to the control group, they would lessen the differences in self-management outcomes between the intervention and control groups, therefore washing out the intervention effect. If the active subjects were assigned to the intervention group, it would cause the ceiling effect because their existing practice would leave little room for improvement by the intervention.
The limitations acknowledged above with respect to study design, intervention content and targeting population also provide direction for future research. First, there is a need for research in rural communities to identify, develop and implement effective palliative care programs to meet the care needs of patients with advanced heart failure and other comorbidities. Second, when developing education information to promote self-management adherence, researchers and clinicians need to take into account the fact that older adults are often juggling multiple treatments for various conditions. Close attention must to be paid to avoid any conflicting information. Rather than adding the education information for various illnesses together, an integrated, comprehensive self-management instruction should be tailored to meet each individuals needs. Last, recognizing the recruitment bias and the impractical requirement of large sample size in conducting randomized control trials, alternative research methods (e.g., mix methods, observational study, secondary analysis with population-level data) should be utilized to provide complementary evidence, leading to better care and better health outcomes.
The challenges of recruiting and retaining rural heart failure patients to participate in research to promote self-management adherence are substantial, which reflects the barriers they face in engaging in self-management practice. These barriers provide opportunities for clinicians and researchers to work together to develop and implement effective programs to promote self- management practice in heart failure patients living in rural communities.
Research reported in this publication was supported by the National Institutes Nursing Research of the National Institutes of Health under award number 1R15NR 13769-01A1. The sponsor had no role in conducting the study, preparing and disseminating the study results. Dr. Lufei Young is the recipient of the funding provided by the National Institutes Nursing Research of the National Institutes of Health. She has full access to the study data and takes responsibility for their integrity and the accuracy of the data analysis.
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Lufei Young, University of Nebraska Medical Center, College of Nursing-Lincoln Division, 1230 “O” St. Suite 131, PO Box 880220, Lincoln, NE 68588-0220, USA E-mail: email@example.com
Young L (2016) Conducting BehavioralIntervention Research in Rural Communities: Barriers and Strategies to Recruiting and Retaining Heart Failure Patients in Studies. NHC 101: 1-8
Research recruitment, Research retention, Behavioral research, Heart failure, Self-management, Rural Health