Histone proteins binds around the DNA and divides into structural units called nucleosomes. It found in eukaryotic cell and participates in gene regulation. The unwind DNA in chromosomes would be very long in the absence of of histones. The diploid cell of human has 23 pairs of chromosomes with 1.8 meter length. In the duplication process of DNA during mitosis the length is 120 micrometers.
The histone proteins exist as dimers which are similar in size. Each histone has three alpha helices linked by two loops. For the interaction between dimers helical structure used particularly in a head-tail manner.
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