Biochemistry

Biochemistry and Modern Applications (ISSN: 2638-7735)

About Journal

Biochemistry and Modern Applications is a peer reviewed Journal, with rapid publication process. The topics like DNA polymerases, Heterochromatin, Ribosome, Non-coding DNA, Cell biology, Metabolism, Nutritional Biochemistry, Medicinal Biochemistry and Hormonal Biochemistry are studied. This is not just limited to above areas. The knowledge related to different biomolecules and their mechanisms can be studied in the journal of Biochemistry and modern applications. This journal provides an open access platform for the young scientists and researchers to share their valuable information regarding the biomolecules and their mechanism.

Biochemistry and Modern Applications is an open access scholarly journal maintaining high standards of scientific excellence and its editorial board ensures a rapid peer review process.

Biochemistry Modern Applications welcome submissions related to above fields. Authors may submit their valuable work at: biochemistry@ewpsjournals.com

Edelweiss publications include rigorous peer review process and high scientific publishing standard to ensure superior contribution to scholarly literature added with high quality production.

Edelweiss publications embrace the philosophy - Connecting the world of scientific community.

The study of chemical processes within and relating to living organisms is known as Biochemistry. This may sometimes be called as Biological chemistry. The complexity of life can be explained using various biochemical processes.

Biochemistry a sub discipline of both biology and chemistry can be divided in three fields; molecular genetics, protein science and metabolism. Over the last decades of the 20th century, biochemistry has become successful in explaining these processes in the living organisms. Biochemical methodology and research covers and develops almost all the areas of life sciences. Understanding of how biological molecules give rise to the processes which occur within living cells and between cells is mainly focused by biochemistry. The study and understanding of tissues, organs, and organism structure and function is also greatly related to biochemistry.

Biochemistry and Modern Applications publishes articles related to above but not limited to it. All the articles related to Biochemistry are published online and are available to the readers worldwide without any Subscription charges. Biochemistry and Modern Applications is the Journal maintained by Edelweiss publications, which ensures of Rapid peer review process with the help of its Editorial Board.

Core fields covered

Cell biology

Cell biology also known as Cytology is a branch of biology. It deals with the structure and function of cell, the basic unit of life. Cell biology journals includes researches on Biochemistry, Molecular biology, Genetics and Immunology.

Cell biology journals offer a stage for researchers in Biochemistry and related subjects. Journal accepts original research papers/case reports/review articles and commentary related to biochemistry. Cell biology journals research is welcome in Biochemistry. Cell biology journals invite the researchers to publish their research work in our journal.

Metabolism

Metabolism refers to the chemical process that occurs in a living organism which is life sustaining. This process involves the conversion of what you eat and drink to energy. This process helps to maintain the living state of cells and organisms. Metabolism is usually the method of conversion of food into energy.

Metabolism review articles published in our journal will undergo rapid peer review process. We try to publish the manuscript within 4-6 weeks of time after submission.

Biochemistry and Modern Applications is a scholarly journal maintaining high standards of Metabolism review articles with scientific excellence. Its editorial board ensures a rapid peer review process.

Nutritional Biochemistry

Nutritional Biochemistry refers to the studies related to nutrients, chemicals, food constituents and their functions in growth and development of humans and mammals and also in the diseases. Nutritional Biochemistry journals involve aspects related to public health, toxicology, pediatrics, food chemistry and physiology.

The researches associated with nutrients and their chemical changes which may improve human health or lead to diseases are included in Nutritional Biochemistry journals.

Nutritional Biochemistry journals such as Biochemistry and Modern Applications invite researchers. We publish research articles/review articles/case reports/mini reviews on nutrition in our journal.

Medicinal Biochemistry

Medicinal Biochemistry is a branch that deals with different molecules and their involvement in human health and diseases. It deals with the chemical compound and their reactions in humans. Medicinal Biochemistry has an important impact on human health and life. Medicinal Biochemistry articles offer a stage for researchers in Biochemistry and related subjects to publish their manuscripts in our journal. Medicinal Biochemistry articles welcome all the topics related to Biochemistry.

Medicinal Biochemistry articles involve modern technologies that help in the diagnosis and treatment of conditions which affects human health.

Hormonal Biochemistry

Hormonal Biochemistry deals with various hormones and their functioning in the body. A chemical released by a cell or a gland into the body is called hormone. These play an important role in cell functioning and sends messages that effect other parts of the organism hence are called as Universal regulators.

Biochemistry and Modern Applications is a scholarly journal maintaining high standards of Hormonal Biochemistry research articles with scientific excellence and its editorial board ensures a rapid peer review process.

 Hormonal Biochemistry research articles includes original research papers/case reports/review articles and commentary related to biochemistry. Hormonal Biochemistry research articles are included in our journal which has rapid peer review process and tries to publish the manuscript within 4-6 weeks of time after submission.

Applications of Bio chemistry in Medicine

Biochemistry study is almost related to the medicine industry. In the improvement in the medicine, the concept of Biochemistry is widely used. Some of the applications of biochemistry in the medicine field include:

1. Physiology

To fully understand the physiology of human body, biochemistry is of great importance to scientists. The biochemical changes occurred in the human body can be understood by scientists using the concept of biochemistry. Disease curing based on the biochemical changes in the body have been lead to develop the best medicine for specific diseases. The working of organs and systems within the body is checked by physiology. How the organs communicate, and how they combine their efforts to make conditions favorable for survival is explained by physiology. Scientists in this field can focus on anything from microscopic organelles in cell physiology. They also focus on wide-ranging topics, such as Eco physiology, which deals with whole organisms and how they adapt to environments. The understanding of the components of our body, their way of communication, and how they keep us alive is improved with the help of physiological research.

Edelweiss Publications review process is done by their active editorial board members only, which help in reducing the timeline for publishing the manuscript after submission.

2. Pathology

Pathology also involves the study of biochemistry. It is usually the study of diseases. Based on the symptoms described, the physician may get the information about the biochemical changes in the patient’s body. The chemical reactions or processes in the body are examined to confirm the patient’s symptoms by the physician. For example, examining the uric acid levels in the body to understand the patient’s symptoms. The term "pathology" is derived from the Greek words "pathos" which means "disease" and "logos" means "a treatise" = a treatise of disease. A pathologist is a medical doctor who is specialized in pathology. The microscopic views of body tissues are detected by experts called pathologists.

Edelweiss Publications Inc is a USA based publisher and journal of Biochemistry and modern applications is part of Edelweiss Publications Inc.

3. Nutritional Deficiency

Good nutrition is really important to have a healthy life. Hence less intake of nutrients or nutritional food leads to various diseases. Nutritional deficiency is also called as malnutrition. Multi vitamins and minerals are consumed by people nowadays to keep them healthy. Scientists use biochemistry as a discipline to formulate the best composition of multi vitamins and minerals. The study of biochemistry helps us to understand the function of vitamins and minerals in our body.

Body development and prevention of diseases requires many different vitamins and minerals. These vitamins and minerals are often known to as micronutrients. These micronutrients are not naturally produced in the body and hence to be taken in the form of diet. Necessary amount of nutrients if not absorbed from the food may lead to a nutritional deficiency. A variety of health problems can be caused due to deficiency of nutrients. Amount of nutrients to be consumed depends on your age.

Edelweiss Publications has a rapid review process, it tries to publish the manuscript within 4-6 weeks of time after submission.

4. Hormonal Deficiency

Hormonal imbalance, can lead to many diseases both in men and women and also in the children. Physicians use the concept of biochemistry to understand about the hormones, their functions and reactions in the human body. Proper medicine can be developed to treat hormonal imbalance using this study. Hormones are called body’s chemical messengers. Hormones are produced in the endocrine glands these chemicals travel along your bloodstream informing tissues and organs what to do. Many of your body’s major processes, including metabolism and reproduction are controlled by hormones. In hormonal imbalance, either you have too much or too little of a certain hormone. Even tiny changes can have serious effects throughout your whole body can be seen with little changes in the hormones. Some of the hormones levels fluctuate throughout your life which may be the result of aging some hormonal changes occur when the endocrine gland gets wrong signal.

Research/review/case reports can be submitted towards Edelweiss Publication journal Biochemistry and modern applications Open Access.

Applications of biochemistry in medical treatment

Nursing discipline also involves the use of Biochemistry. To monitor the progress of patients regularly in the hospital, biochemistry can be used. The best treatment to the patients based on their conditions can be developed using biochemistry. The diagnosis of clinical conditions of the patients is made easier to the nurses using biochemistry. These are some other possible applications of biochemistry:

1. Kidney Function Test

The kidney function is related to the biochemistry study. If there is any problem in the kidney, you may undergo the urine test. This urine test helps us to detect the change in PH, color of the urine or other matters in the urine. The fundamental study that covers this kind of treatment is Biochemistry.

2. Blood Test

Biochemistry study is also involved in the concept of blood test. The patient’s condition is understood by the analytical test for blood glucose. For example, in the diabetes patient, the stages of the diabetes can be indicated by this kind of test. There are also other tests for diabetic patients known as the ketones bodies in urine test. The last stage of diabetes is indicated by ketone bodies or ketone urea. These kinds of substances in the urine can be tested by the study of biochemistry.

3. Liver Function Tests

The study of liver can also be understood using biochemistry. Biochemistry helps us to understand how the liver function of liver, the type of disorder which is likely to affect liver and the effect of certain medicines to the liver can be understood with the help of biochemistry.

4. Serum Cholesterol Test

Biochemistry can be used to check the cholesterol levels in the blood. Your health condition can be indicated by the cholesterol and other lipoproteins in the blood.

5. Pregnancy Test

The presence of HCG or human chorionic gonadotropin hormone indicates pregnancy. As soon as the implantation of embryo into the uterine walls this type of hormone is made by the placenta. The urine or blood sample detects the presence or absence of this hormone. Thanks to biochemistry to help us discover this hormone.

6. Ames Test

The test applied to Salmonella bacteria is Ames test. The growth of the bacteria in the body is detected or measured by this test. The mutation of the DNA structure by bacteria can be understood and screened with the help of certain chemicals. The indication of cancer potential in our body based on chemical reactions can also be tested.

7. Breast Cancer Screening

The mutations in two genes consisting of Breast Cancer-1 gene (BRCA1) and the Breast Cancer-2 gene (BRCA2) is examined by conducting breast cancer screening. This examination can be conducted with the help of biochemistry concept.

8. PKU Test

A metabolic disease in which the individual is missing an enzyme named phenylalanine hydroxylase which is known as PKU or Phenylketonuria. Mental retardation can occur which is due to the absence of this enzyme.

Current issue articles

Hantzsch Reaction as a Method for Spectrofluorimetric Analysis of Penicillin G

Author(s): Mohamed A.El Hamd, Ahmed A.H. Abdellatif*

Abstract

A sensitive, selective, and validated spectrofluorimetric method is being described for the determination of penicillin G. The method utilizes this drug (as a source of the amine moiety) to react with acetylacetone and formaldehyde through the Hantzsch reaction. The faint yellow product of dihydropyridine derivatives was measured at an emission wavelength of 481 nm (after excitation at 416 nm). Linear calibration graphs were obtained in the range of 0.2-200 μg/mL. The experimental limits of detection and quantitation were 0.170 and 0.515 μ/mL, respectively. The relative standard deviation (n=5) at the 100 μg/mL level were 6.11 for intra-day precision and 9.42 for inter-day precision. The method was successfully applied in the analysis of pharmaceutical formulation; the recovery was quantitative, and the result obtained agreed with those

Metabolic Link of Human Milk: Effects on Weight, Length and Body Mass Index (BMI)

Author(s): Salah Ahmed Shoheb, Mohamed A.El-Gamasy*

Abstract

Background: Breast milk adiponectin could play a role in regulation of infants, growth during lactation.

Aim of work: To evaluate adiponectin concentration in human milk and to investigate its relationship with serum adiponectin concentration in lactating mothers and their breastfed infants and with anthropometric parameters of infants and mothers.

Materials and methods: 60 healthy term infants and their healthy lactating mothers are included at infant age of one month then repeated again at the age of 4 months. All subjects included in this study were subjected to history, clinical examination, investigations including serum level of adiponectin of infants and their mothers by RIA test, Human milk level of adiponectin by ELIZA test.

Results: There was a significant decrease in serum adiponectin of infant and mothers and maternal breast milk at age of 4 months (48 ± 6.5,13 ± 1.7, 5.3 ± 2 respectively) when compared to them at the age of 1 month(62.6 ± 1.5, 21.4 ± 5.6, 13.4 ± 3.8 respectively). There was a significant negative correlation between maternal serum adiponectin and BMI of mothers. There was a significant negative correlation between infant serum adiponectin and their weight and length of infants at age of 1 month and at age of 4 months.

Conclusions: There’s a metabolic link between mothers and their infants through breast milk during 1st to 6th months of life. A gradual decline in adiponectin level in maternal breast milk is associated with gradual increase in infant growth up to 6 months of age.



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