According to WHO, term quality control refers to the total of all procedures undertaken to make sure the identity and purity of a selected pharmaceutical. Quality control is a vital operation of the pharmaceutical business. Medication should be marketed as safe and therapeutically active formulations whose performance is consistent and predictable. It not solely protects the manufacturer against compensation claims, however conjointly guarantees the patient a secure and effective product. Quality control measurements embrace stability testing of the drug formulation, dissolution testing and analysis of raw materials and synthesis product majorly. The pharmacies that perform unsuitably as drug producing corporations however are not legally required to adhere to federal drug producing laws. Rather, they perform underneath additional lenient state policies that govern their operation, however do not enforce quality control analysis. This lack of regulation and oversight has led to many vital microorganism outbreaks that have resulted in multiple deaths from use of contaminated canal steroids, cardioplegia solutions, and blood vessel medication. These events highlight the importance of effective pharmaceutical sterility procedures further because they would like for updated regulative management policies governing the operation of change of integrity pharmacies. During this article, we are going to discuss current practices and problems related to pharmaceutical internal control analysis, however these will have an effect on patient health and safety, and what may well be done to remedy the difficulty.