Neuronal lineage marker
Neuronal lineage marker is an endogenous tag or marker that is expressed in different cells along neurogenesis and differentiated cells such as neurons. A neuronal lineage marker can be either DNA, mRNA or RNA expressed in a cell of interest. It can also be a protein tag, as a partial protein, a protein or an epitope that discriminates between different cell types or different states of a common cell. Cell markers are very valuable tools for examining the function of cells in normal conditions as well as during disease.
The techniques used for its detection can be immunohistochemistry, immunocytochemistry, methods that utilize transcriptional modulators and site-specific recombinases to label specific neuronal population,in situ hybridization or fluorescence in situ hybridization.
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