Adie syndrome also called Holmes-Adie syndrome is a neurological disorder characterized by a tonically dilated pupil. It is frequently seen in females with absent knee or ankle jerks and impaired sweating. It is caused by damage to parasympathetic nerve innervation of the eye, usually by a viral/bacterial infection which causes inflammation, and affects the pupil of the eye and the autonomic nervous system.
Symptoms includes mydriasis, loss of deep tendon reflexes, and abnormalities of sweating, other hyperopia, photophobia and difficulty reading. Some individual with Adie syndrome may also have cardiovascular abnormalities and it can be diagnosed by CT scans and MRI scans
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