Biochemistry

Biochemistry and Modern Applications (ISSN: 2638-7735)

Mutations

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Mutations

In biology, a mutation is the permanent modification of the nucleotide sequencing of the genome of a life form, virus or extra chromosomal DNA or other hereditary elements. Mutations result from mistakes during DNA replication (particularly during meiosis) or different sorts of damages to DNA, (for example, might be caused by introduction to radiation or cancer-causing agents), which then may undergo error-prone repair (particularly micro homology-mediated end joining), or cause an error during different repairs or else may cause a error during replication (translesion synthesis). Mutations may likewise result from insertion or deletion of portions of DNA because of mobile genetic elements. Mutations could possibly deliver noticeable changes in the detectable attributes (phenotype) of a living being. Mutations have an impact in both normal and abnormal natural procedures including: evolution, malignant growth, and the improvement of the immune system, including junctional diversity. The genomes of RNA infections depend on RNA instead of DNA. The RNA viral genome can be twofold stranded (as in DNA) or single stranded. In a portion of these infections, (for example, the single stranded Human Immunodeficiency Virus) replication occurs rapidly and there are no mechanisms to check the genome for precision. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as, DNA repair to avoid or correct mutations by by reverting the mutated sequence back to its original state..

Biochemistry and Modern Applications is a peer reviewed Journal, with rapid publication process. The topics like DNA polymerases, Heterochromatin, Ribosome, Non-coding DNA, Cell biology, Metabolism, Nutritional Biochemistry, Medicinal Biochemistry and Hormonal Biochemistry are studied. This is not just limited to above areas. The knowledge related to different biomolecules and their mechanisms can be studied in the journal of Biochemistry and modern applications. This journal provides an open access platform for the young scientists and researchers to share their valuable information regarding the biomolecules and their mechanism.

Editorial Board List

Professor
Egyptian Petroleum Research Institute (EPRI)
Egypt

Professor
Department of Medical Biology
Nigde Ömer Halisdemir University
Turkey
Assistant Professor 
Department of Eastern Medicine
Faculty of Science and Technology
Government College University 
Faisalabad,Pakistan
Researcher
Plant Science and Biotechnology 
Federal University of Agriculture Makurdi 
Nigeria
Assistant Professor
Department of life Sciences
Alfaisal University
Riyadh, Kingdom of Saudi Arabia
Professor
College of Life Science and Bioengineering
Beijing University of Technology 
Beijing, China
Professor
Department of Dermatology & Plastic Surgery
Kumamoto University
Kumamoto, Japan
Dalian Medical University
China

Scientific Researcher
University of Bari
Italy
Associate Professor
Universiti Putra Malaysia
Malaysia
Professor
Department of Medical Biochemistry 
Firat University
Turkey
Assistant Professor
Department of Chemistry
Govt. Degree College
India

Jiban Shrestha
Scientist
Nepal Agricultural Research Council
Agriculture Botany Division
Nepal

Highly Accessed Articles List

Editorial : Lysine Methylation of Non-Histone Proteins

Byron Baron


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Editorial : Science Can Still Captivate Us All

Adolfo Rivero-Müller


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Research Article : Hantzsch Reaction as a Method for Spectrofluorimetric Analysis of Penicillin G

Mohamed A. El Hamd , Ahmed A. H. Abdellatif


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Editorial : A Case of Complete Recovery from an Allergic Disease

Kimihiko Okazaki


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Research Article : Metabolic Link of Human Milk: Effects on Weight, Length and Body Mass Index (BMI)

Salah Ahmed Shoheb, Mohamed A.El-Gamasy


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Research Article : Current State of Art of Diaminomalenonitrile Based Synthetic Receptors for Ion Sensing With Bio Applications: Mechanistic, Sensing and Photophysical Aspects

Masood Ayoub Kaloo and Bilal A Bhat


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Review Article : The Role of Human Coactosin-Like Protein in Neurodegenerative Disorders

Y Anu Shanu, Antonio Lauto, Simon J Myers


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Research Article : Synthesis of Some Novel Chalcone Derivative Via Microwave Method & Its Antimicrobial Activity

Nilesh Pandya, Tejas Gandhi, KR Desai


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Research Article : Neuro Effects of Opioids on the Human Brain

Clairmont Griffith and Bernice La France*


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Research Article : Phytochemistry and Antioxidant Activities of the Methanolic Leaf Extract of Clerodendrum splendens (Lamiaceae)

Nganso Ditchou Yves Oscar, Amang A Ngnoung GA, Soh Desire, Simo Nemg Fredy Brice and Nyasse Barthelemy


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Research Article : In Vitro Phytochemical Screening and Antioxidant Activity of Jamun (Eugenia jambolana Linn) Plants Parts Collected from Lahore, Pakistan

Nureen Zahra, Momna Nadir, Arif Malik, Ayesha Shaukat, Asia Parveen and Muhammad Tariq


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Research Article : A New Potent Anti-cancer Corosolic Ester Identified from the Super Miracle Plant Hippophae rhamnoides (Sea buckthorn)

Irfan Ali, Noor-ul-Ain Zahra, Reazuddin, Huma Sharif, Mudassar and Huma Aslam Bhatti


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Research Article : Assessment of Programmed Cell Death of Aspergillus flavus by Triggered Cysteine-dependent Aspartate-directed Proteases (Meta-caspase3) Lethality Mechanism of Novel Compounds Isolated from Ethyl Acetate Extract of Spondias mombin

Oludare Temitope Osuntokun, Olaposi I Omotuyi, Anthonia O Oluduro, Thomas O Idowu

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Commentary : CRISPR CUREs: Running with Molecular Scissors in the Classroom
Emily R Siniscalco and Te-Wen Lo
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Research Article : Comparative Antiseptic Effects of Some Locally Used Plant Products on Isolated Skin Microorganisms

 Olasan JO, Yandev D, Aguoru CU, Ukaonu C and Obaje C


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