Dopamine is an organic chemical that plays a very important role within the brain and body. It is an amine which is synthesized by removing a chemical group from a molecule of its precursor chemical L-DOPA, that is synthesized within the brain and kidneys. This can be synthesized in plants and animals. Within the brain, Dopamine neurotransmitter functions as a neurotransmitter—a chemical free by neurons to send signals to different nerve cells. The brain includes many distinct dopamine neurotransmitter pathways, one among that plays a serious role within the psychological feature element of reward-motivated behavior. The anticipation of most styles of rewards will increase the extent of dopamine neurotransmitter within the brain, and lots of addictive medicine increase dopamine neurotransmitter unharness or block its uptake into neurons following unharness. Different brain dopamine neurotransmitter pathways area unit concerned in control and in dominant the discharge of varied hormones. Pharmacovigilance and Pharmacoepidemiology Journal aim is to publish high quality research in the discipline of Pharmacovigilance by providing encouragement for editors, reviewers, authors, and readers to have an uninterrupted scientific communication.