Drug potency is the amount of drug required to produce a given percentage of its maximal effect, irrespective of the size of maximal effect. A drug can have high potency but poor efficacy, meaning that response is seen at very low doses and remains small even at high doses. Drug potency is seldom an important clinical consideration. In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity. A highly potent drug evokes a given response at low concentrations, while a drug of lower potency evokes the same response only at higher concentrations. The potency depends on both the affinity and efficacy.
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