Central-acting agents are also called as central adrenergic inhibitors, central alpha agonists and central agonists. Central-acting agents lower the heart rate and reduce the blood pressure. They work by preventing brain from sending signals to the nervous system to speed up the heart rate and narrow the blood vessels. As a result, heart doesnt pump as hard and blood flows more easily through the blood vessels. Clonidine, Guanfacine and Methyldopa are the examples of central-acting agents.
Central-acting agents used to prevent, treat or improve symptoms in conditions, such as:
• Attention-deficit/hyperactivity disorder (ADHD)
• Hot flashes
• Drug withdrawal