Biochemistry

Biochemistry and Modern Applications (ISSN: 2638-7735)

Editorial :

A Case of Complete Recovery from an Allergic Disease


Kimihiko Okazaki

Full-Text

According to the traditional concept of the contemporary Immunology, neither autoimmune diseases nor allergic diseases can be cured completely. Nevertheless, a fortunate coincidence led me to discovery of a novel concept that eliminations of the causes of these diseases are possible. In other words, combinations of pathogenic antibodies with responsible cells, namely, cytolytic T lymphocytes in cases of autoimmune diseases and mast cells in cases of allergic diseases, can be decomposed by replacing the pathogenic antibodies with non-specific antibodies. In more detail, intradermal injections with a non-specific antigen preparation induce production of non-specific antibodies in the body of the patient. Repetitions of the injections bring about an accumulation of them. Accumulated non-specific antibodies will occupy most of the receptors on the surface of responsible cells. When the accumulation reaches the sufficient level, virtually no pathogenic antibodies would remain on the receptors. That is, no causes of the diseases remain. Naturally, where there is no cause, there is no disease. Details are demonstrated elsewhere [1].

 A 68-year-old woman (K.I.) visited my clinic on September 16, 2016. She told me that she used to suffer from persistent cough when she caught cold in her childhood. She also told me that she had been extraordinarily sensitive to smoke since she was 53 years of age and that once she starts coughing, she can never stop it for a considerably long time. I diagnosed her as bronchial asthma and injected her intradermally with 0.1ml of 10 to the 36-fold with saline diluted Neurotropin, a product of Nippon Zohki Pharmaceutical Company(Osaka), consisting of an extract of rabbit skin inflamed by inoculation of Vaccinia virus, at 1~34 day intervals during the period from September 16, 2016 until January 30, 2017. The total number of injections was 25. Her blood-test, which was performed on January 30, 2017, revealed that she was not allergic against any potential allergens. On the same day, she told me that she sometimes coughed but not continuously. The site of the injections was her navel-edge because of the skin thickness,which may increase the injected antigen’s stay-time in the skin resulting in increase in the amount of produced non-specific antibodies. 

Reference

1. Okazaki K. Therapeutic significance of non-specific antigens as anti-allergic and anti-autoimmune agents (2009) Pharmacometrics 76: 105-107.

Keywords

Antigens, Antibodies, Immunology, Pathogens, Auto immune



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