Edelweiss: Cancer Open Access journal emphasize in publishing the original scholarly articles related to cancer, Trophoblast glycoprotein articles, cancer immunotherapy articl"> Edelweiss cancer Open Access is interested in publishing research, review manuscripts covering all aspects of cancer. We invite manuscripts which are novel and highly innovative in detecting or curing cancer of all forms. Clinical trial studies, research on new therapeutic agents, drugs and chemicals and new concepts for detection and treatment of cancer.

Edelweiss: Cancer Open Access

Trophoblast glycoprotein

Image explains about Trophoblast glycoprotein
Trophoblast glycoprotein

Trophoblast glycoprotein, also known as TPBG, 5T4, Wnt-Activated Inhibitory Factor 1 or WAIF1, is a human protein encoded by a TPBG gene. TPBG is an antagonist of Wnt/β-catenin signalling pathway.

5T4 is an antigen expressed in a number of carcinomas and referred to as an oncofetal antigen due to its expression in trophoblast glycoproten. 5T4 is found in tumors including the colorectal, ovarian, and gastric. Its confined expression appears to give 5T4 the potential to be a target for T cells in cancer immunotherapy. 5T4 is also the target of the cancer vaccine TroVax which is in clinical trials for the treatment of a range of different solid tumour types

Edelweiss: Cancer Open Access is an open access journal which aims to publish most complete and genuine source of information in the form of short commentary, mini review, case report, related, but not limited to above areas and making them available freely through online without any subscriptions and restrictions to researches worldwide

Editorial Board List

Department of Diagnostic Pathology
School of Medicine
University of Toyama
Department of Biochemistry
Kafrelsheikh University
Lead Imaging Engineer
Departments of Diagnostic Radiology and Cancer Systems Imaging
Division of Diagnostic Imaging
University of Texas, Anderson Cancer Center
Consultant Urologist 
Mansoura University 

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