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Cancer stem cells are cancer cells that possess characteristics as normal stem cells, which have the ability to give rise to all cell types. CSCs are therefore tumorigenic and generate tumors through the stem cell processes and are self-renewal and differentiation into multiple cell types. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for patients with metastatic disease. The efficacy of cancer treatments is, in the initial stages of testing, often measured by the ablation fraction of tumor mass.
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