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The three-membered ring heterocycles containing single atoms of nitrogen, oxygen, and sulfur aziridine, oxirane or (epoxides- most commonly encountered three-membered heterocycles), and thiirane respectively and their derivatives can all be prepared by nucleophilic reactions. Thus, aziridine is formed by heating β-aminoethyl hydrogen sulfate with a base (in this case Y is -OSO3H). Epoxides are easily prepared by reaction of alkenes with peracids, usually with good stereospecificity. Addition reactions proceeding by electrophilic or nucleophilic opening of the ring constitute the most generally used reactions.
Journal of heterocyclics is a scholarly journal that aims to publish most complete and reliable source of information on the findings and current developments in the form of original Research, Review, Opinion articles, Case reports, Mini review, and Short commentaries. Journal of heterocyclics is an scholarly open access maintaining high standards of scientific excellence and its editorial board ensures rapid peer review process.
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