Pharmacovigilance and Pharmacoepidemiology (ISSN: 2638-8235)
Editor
Biography
I am an Assistant Professor of Medicine currently working at Mayo Clinic in Rochester, Minnesota. I graduated the School of Medicine at the University of the Republic, Montevideo, Uruguay in 2004. I was involved in clinical practice in Montevideo until December of 2008, when my interest in research drove me to the Mayo Clinic to work as a Research Trainee, Research Fellow, Senior Research Fellow, and now as an Associate Consultant in the Division of Nephrology and Hypertension.
Over the past years, I have published more than 50 peer-reviewed papers and more than 60 abstracts in prestigious scientific journals in the field of renal and cardiovascular diseases, 3 book chapters, and served as a reviewer for several peer-reviewed journals with a worldwide circulation, such as Hypertension and Circulation. I have also presented multiple oral and poster presentations at recognized scientific meetings such as the American Society of Nephrology Renal Week, which is the world’s premier nephrology meeting.
I have received several awards including a Post-doctoral Fellowship Award and a Scientist Development Grant from the American Heart Association, the Panitch Career Development Award in Hypertension Research and the “Outstanding Research Fellow Award 2012” from the Department of Medicine at Mayo Clinic, a “Top Oral Abstract by Trainees for the ASN Kidney Week 2012”, and the “Top Scoring abstract in all 16 American Heart Association’s Specialty Conferences in 2012”.
My research is funded by the NIH, the Mayo Clinic Centers for Regenerative Medicine and Clinical and Translational Science.
Research Interest
My research interests have focused on understanding the pathogenesis of renal and cardiac injury due to atherosclerotic renovascular disease (ARVD), and the development of novel treatment strategies to improve blood pressure and renal outcomes after revascularization in swine ARVD. These studies include the application of state-of-the-art imaging techniques (multi-detector computer tomography, micro-computer tomography, magnetic resonance imaging, etc.) in animal models and in humans. In addition, I have been involved in several projects aimed to elucidate the deleterious effects of inflammation in the ARVD kidney, and the development of treatment options (stem cells, progenitor cells, anti-apoptotic drugs, etc.) to attenuate microvascular rarefaction and loss beyond the stenotic lesion.
Furthermore, I have explored the role of mitochondria as therapeutic targets in cardiovascular disease. My studies have demonstrated that mitoprotection preserves function and decreases fibrosis in the porcine stenotic-kidney, demonstrating a novel therapeutic potential for this intervention in improving renal outcomes in experimental ARVD.
Keywords
- Pharmacokinetics
- Pharmacovigilance
- Pharmaoepidemiology
- Drug discovery
- Adverse drug reaction
- Clinical pharmaoclogy
- Environmental pharmacology
- Clinical trials
- Clinical data management
- Regulatory affairs
- Pharmacodynamics
- Quality control
- Biopharmaceutical drug
- Drug development
- Generic drug
- Phamacotherapy
- Hematology
- Pathophysiology
- Pharmacogenomics
- Drug abuse
- Evidence based medicine
- Drug addiction
- Drug intolerance
- Antiviral drugs
- Drug interaction
- Telemedicine
- Polypharmacy
- Telepharmacy
- Biological target
- Therapeutic drug monitoring
- Microencapsulation
- Signal transduction
- Drug testing
- Risk management
- Safety monitoring
- Incidence rate
- Drug Utilization Review
- Prescription event monitoring
- Attributable Risk
- Vaccine safety
- Drug adherence
- Relative Risk
- Haematology
- Adverse drug event
- Biopharmaceutical science
- Pharmacoeconomics
- Cost-effectiveness analysis
- Antibiotics
- Probiotics
- Antiretroviral therapy
- Post marketing surveillance
- Clinical research
- Regenerative medication
- Dopamine
- Antidiabetic drugs
- Drug toxicity
- Drug metabolism
- Prodrug
- Clinic management systems
- Drug detoxification
- Pharmaceutical formulation
- Quality assurance
- Validation
- Neuropharmacological study
- Pharmacotherapy
- Medication error
- Translational medication
- Psychoactive drug
- Pharmacognosy
- Pharmacophore
- Drug stability
- Targeted drug delivery
- Drug evaluation
- Quality packing
- Medical guideline
- Over-the-counter medicine
- Prescription writing
- Language barrier for community pharmacist
- Antimicrobial resistance
- Antibiotic prophylaxis
- Community pharmacists
- Health literacy
- Cellular Medicine
- Cell therapy
- Drug Dosage formulation
- Gene therapy
- Genetic polymorphism
- Personalized medicine
- Pharmacogenomic biomarkers
- PROTEOMICS - Clinical Applications
- Drug Efficacy
- Drug Potency
- Clinical audit
- Clinical ethics
- Aquatic toxicology
- Drug safety regulations
- Missed dose
- Medical literature
- Poisonous Effects
- Internal medicine
- Occupational medicine
- Drug overdose
- Postmarketing surveillance
- Premarketing Clinical Trial Safety
- Delayed drug effects
- Automated databases
- Electronic Health Record
- Medical record databases
- Gene-Gene Interaction
- Gene-drug interaction
- Bioethical issues
- Patient Reported Outcome
- White coat adherence
- Drug utilization
- Medical occurrence report
- Pharmaceutical drug
- Prescription drug
- Prescription drug abuse
- Drug addictions
- Drug withdrawal symptoms
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