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Insulin action:Insulin initiates action by binding to a glycoprotein receptor on the surface of the cell. This receptor consists of an alpha-subunit, which binds the hormone, and a beta-subunit, which is an insulin-stimulated, tyrosine-specific protein kinase. Activation of kinase generates a signal that results in insulins action on glucose, lipid, and protein metabolism. Both genetic and acquired abnormalities in the number of insulin receptors, the activity of the receptor kinase, and the various post-receptor steps in insulin action occur in disease states leading to tissue resistance to insulin action.
Journal of Obesity and Diabetes emphasize in publishing the original scholarly articles related to Obesity and Diabetes worldwide. The journal follows rapid review process with the Eminent Editorial Board
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