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Peripheral Insulin Resistance (PIR) is considered as a pathological condition in which cells fail to respond normally to the hormone insulin. Simply stated, Insulin resistance is a condition in which multiple tissues in the human body become resistant to the effects of insulin. It typically develops with obesity and the onset of type 2 diabetes in which circulating insulin levels are frequently increased. Insulin resistance is caused by lipid overload, resulting from either a high fat diet or insufficient fat burning through movement. A high intake of dietary fat causes lipid overload and insulin resistance in the muscle and liver. Sucrose (white table sugar) also increases liver insulin resistance
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Related article links for Peripheral Insulin Resistance will appear here as matching content is published in Journal of Obesity and Diabetes (ISSN: 2638-812X). Readers can also browse the journal archive and current issue for connected research.