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An oncovirus is a cancer cause virus and often called oncornaviruses due to their RNA virus origin. Oncoviruses can control cell cycle mechanisms of Retinoblastoma protein. Some viruses are tumorigenic when they infect a cell and persist as circular episomes or plasmids, replicating separately from host cell DNA. Other viruses are only carcinogenic when they integrate into the host cell genome as part of a biological accident, such as polyomaviruses and papillomaviruses. Viruses with a DNA genome, such as adenovirus, and viruses with an RNA genome, like the Hepatitis C virus, can cause cancers, as can retroviruses having both DNA and RNA genomes. In many cases, tumor viruses do not cause cancer in their native hosts but only in dead-end species. Eg, adenoviruses do not cause cancer in humans they only become tumorigenic when infected into certain rodent species, such as Syrian hamsters.
Edelweiss: Cancer Open Access is an open access journal which aims to publish most complete and genuine source of information in the form of short commentary, mini review, case report, related, but not limited to above areas and making them available freely through online without any subscriptions and restrictions to researches worldwide
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