Pharmacovigilance and Pharmacoepidemiology (ISSN: 2638-8235)

Pharmacokinetics is a branch of pharmacology which deals with the movement of drug in the living organisms. The substance which includes any chemical xenobiotic such as pesticides, cosmetics, pharmaceutical drugs, food additives etc. It analyze the chemical metabolism, discover the fate of a chemical, act accordingly and the drug is excreted from the body. The criteria of the drug takes place in three steps.

• Absorption – is the process in which the drug enters into the body and absorbed.
• Distribution – the drug rapidly circulates into the blood after the absorption, later the drug moves into the body tissues from the blood.
• Metabolism – Drug can be metabolized by reduction, oxidation, hydration, conjugation, hydrolysis and condensation. The main goal of drug is to eliminate from the body easily. The metabolism differs from person to person, genetic factors influence the rate of the drug metabolism individually.
• Excretion – is a process in which the drug must be removed from the body. In some cases, the drug accumulates the body tissue which may cause side effects.