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Goodpasture syndrome is also called as anti-glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpastures antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death. Currently, the preferred term for both conditions is anti-GBM antibody disease. Circulating antibodies are directed against the collagen of the part of the kidney known as the glomerular basement membrane, resulting in acute or rapidly progressive glomerulonephritis. Nursing and Health Care is an open access journal with rapid publication process, high quality manuscripts with innovative research which covers all the aspects of Nursing and Health Care.
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